Internal ear diseases and complement.

Complement and glomerular diseases.

The complement pathway is a central part of the innate immune system and also modulates adaptive immunity. It is implicated in the pathogenesis of glomerular disease by a number of clinical findings. These include the presence of complement components in renal biopsy samples, decreases in circulating levels indicating consumption, the presence of autoantibodies to complement proteins and the as...

Diseases of the Ear

Diseases of the Ear

Thb number of text-books on diseases of the ear has had many additions within the last few years. This comprehensive work of forty-four chapters is a notable addition to the list, written as it is in collaboration by the well-known Manchester aural surgeon and London aural pathologist. In range of subject and depth of exposition it rivals Pulitzer's classical work, but is much better illustrate...

Diseases of the Ear

Complement: Deficiency Diseases

Individuals with genetically determined complement deficiencies have a variety of clinical presentations. Most patients present with an increased susceptibility to infection, otherswith a variety of rheumatic diseases, still others with angio-oedema, and in rare instances, patients may even be asymptomatic. The elucidation of the pathophysiological basis for the different clinical presentations...